KLRG1 MARKS TUMOR-INFILTRATING CD4 T CELL SUBSETS ASSOCIATED WITH TUMOR PROGRESSION AND IMMUNOTHERAPY RESPONSE

KLRG1 marks tumor-infiltrating CD4 T cell subsets associated with tumor progression and immunotherapy response

Current methods for biomarker discovery and target identification in immuno-oncology rely on static snapshots of tumor immunity.To thoroughly characterize the temporal nature of antitumor immune responses, we developed a 34-parameter Health spectral flow cytometry panel and performed high-throughput analyses in critical contexts.We leveraged two di

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R/BHC: fast Bayesian hierarchical clustering for microarray data

Abstract Background Although the use of clustering methods has rapidly become one of the standard computational approaches in the literature of microarray gene expression data analysis, little attention has been paid to uncertainty in the results obtained.Results We present an R/Bioconductor port of a fast novel algorithm for Bayesian agglomerative

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